Starting on:
Apr 22, 2021
Ending on:
Apr 22, 2021
Moderator(s):
Venue:
THE KAREN HOSPITAL
Max Credits:
3 Points
Provider:
Karen Hospital
Claim Points
Apr 22, 2021
Ending on:
Apr 22, 2021
Moderator(s):
THE KAREN HOSPITAL
Max Credits:
3 Points
Provider:
Karen Hospital
Claim Points
JOURNAL CLUB - 22/04/2021
Starting on:
Apr 22, 2021 8:00 AM
Apr 22, 2021 8:00 AM
Ending on:
Apr 22, 2021 9:30 AM
Apr 22, 2021 9:30 AM
Venue:
THE KAREN HOSPITAL
THE KAREN HOSPITAL
Description
Angiotensin-neprilysin inhibition versus enalapril in heart failure - We compared the angiotensin receptor-neprilysin inhibitor LCZ696 with enalapril in patients who had heart failure with a reduced ejection fraction.
Objectives
the inhibition of both the angiotensin II receptor and neprilysin with LCZ696 was more effective in reducing the risk of death from cardiovascular causes or hospitalization for heart failure than was ACE inhibition with enalapril.
LCZ696 was also superior to enalapril in reducing the risk of death from any cause and reducing symptoms and physical limitations of heart failure.
The magnitude of these advantages of LCZ696 over ACE inhibition was highly significant and clinically important, particularly since the drug was compared with a dose of enalapril that has been shown to reduce mortality, as compared with placebo.
Presenters
-
Dr.
Shammah Muyaka
Medical Officer
The Karen Hospital