JOURNAL CLUB - 06/05/2021
Starting on:
May 6, 2021
Ending on:
May 6, 2021
Moderator(s):
Venue:
THE KAREN HOSPITAL
Max Credits:
3 Points

Provider:
Karen Hospital
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JOURNAL CLUB - 06/05/2021

Starting on:
May 6, 2021 8:00 AM
Ending on:
May 6, 2021 9:30 AM
Venue:
THE KAREN HOSPITAL

Description

Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study.

Objectives

- Ivabradine should be considered to reduce the risk of HF hospitalization in patients in sinus rhythm with an EF â?¤ 35%, a heart rate remaining â?¥ 70bpm and persisting symptoms (NYHA class II-IV) despite treatment with evidence-based dose of beta blocker (or maximum tolerated dose below that), ACE inhibitor (or ARB), and an MRA (or ARB) (class IIa, level B). - Ivabradine may be considered to reduce the risk of HF hospitalization in patients in sinus rhythm with an EF â?¤ 35% and a heart rate â?¥ 70bpm who are unable to tolerate a beta-blocker. Patients should also receive an ACE inhibitor (or ARB) and an MRA (or ARB). (class IIb, level C). - Most cardiovascular endpoints (death from heart failure, hospital admission for heart failure, any cardiovascular admission, and the secondary composite of cardiovascular death, hospital admission for heart failure, or non-fatal myocardial infarction) were significantly reduced by ivabradine.

Presenters

  1. Dr. JANE WAVINYA
    MEDICAL OFFICER
    The Karen Hospital

  2. Dr. LAMIN JAITEH
    MEDICAL OFFICER
    The Karen Hospital

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